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药靶细胞株 > kinase激酶细胞株 > CBP73271EML4-ALK V1 G1202R/L1196M /BaF3

EML4-ALK V1 G1202R/L1196M /BaF3
名称 EML4-ALK V1 G1202R/L1196M /BaF3
型号 CBP73271
报价
特点 EML4-ALK V1 [G1202R/L1196M] /BaF3,母细胞:BaF3,冻存条件:90% FBS+10% DMSO,培养基:1640+10%FBS+2ug/ml puromycin
  • 详细内容

 

CBP73271
I. Introduction

Cell Line Name:

EML4-ALK V1 [G1202R/L1196M] /BaF3

Gene Synonyms:

EML4, ALK

Host Cell:

Ba/F3

Stability:16 passages

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

1640+10%FBS+2ug/ml puromycin

Mycoplasma Status:

Negative

 
II.Background

EML4-ALK results from the fusion of EML4 and ALK, resulting in constitutive kinase activity, transformation in cultured cells, and tumor activity in mouse models (PMID: 19064915, PMID: 17625570). EML4-ALK fusions have been associated with non-small cell lung cancer (PMID: 26755435).

 
III. Representative Data

1. WB of EML4-ALK V1 [G1202R/L1196M] /BaF3 expression

Figure 1  Protein Expression of ALK detected by antibody.

 

2. Sanger of EML4-ALK V1 [G1202R/L1196M] /BaF3

Figure 2 .EML4-ALK V1 [G1202R/L1196M] /BaF3 Fusion

Figure 3 . EML4-ALK V1 [G1202R/L1196M] /BaF3 [G1202R/L1196M]

 

3. Anti-proliferation assay

Figure 4 . CTG Proliferation Assay of BaF3 EML4-ALK V1 [G1202R/L1196M] (C1).

 

 

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