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药靶细胞株 > kinase激酶细胞株 > CBP73231KIF5B(E15)-RET(E12) G810R/BaF3

KIF5B(E15)-RET(E12)  G810R/BaF3
名称 KIF5B(E15)-RET(E12) G810R/BaF3
型号 CBP73231
报价
特点 KIF5B(E15)-RET(E12) [G810R]/BaF3,母细胞:BaF3,冻存条件:90% FBS+10% DMSO,培养基:1640+10%FBS+2ug/ml puromycin
  • 详细内容

 

CBP73231
I. Introduction

Cell Line Name:

KIF5B(E15)-RET(E12)  [G810R]/BaF3

Gene Synonyms:

KIF5B、G810R

Host Cell:

BA/F3

Stability:16 passages

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

1640+10%FBS+2ug/ml puromycin

Mycoplasma Status:

Negative

 
II.Background

KIF5B, kinesin family member 5B, is a microtubule motor protein involved in cargo transportation (PMID: 12743033), including lysosome and mitochondria transportation (PMID: 30058692). KIF5B fusions with RET (PMID: 22327624, PMID: 32094155), MET (PMID: 29284707), and ALK (PMID: 21656749, PMID: 21757253) have been frequently identified in lung cancer (PMID: 22327623), and Kif5b expression has been associated with poor prognosis in oral squamous cell carcinoma (PMID: 30058692).

 
III. Representative Data

1. WB of KIF5B-RET (G810R)/BaF3

CBP73231 WB.png

     

2.Sanger of KIF5B-RET (G810R)/BaF3


CBP73231 sanger1.jpg

CBP73231 sanger2.jpg


3. Anti-proliferation assay

Figure 4. CTG Proliferation Assay of BaF3 KIF5B-Ret (S) G810R (C3).


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