名称 | NPY4R/Ga16/CHO |
型号 | CBP71328 |
报价 | ![]() |
特点 | NPY4R/Ga16/CHO 冻存条件:90% FBS+10% DMSO |
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CBP71328 | |
I. Background | |
NPY4R (Neuropeptide Y Receptor Y4) is a Protein Coding gene. Diseases associated with NPY4R include Alzheimer Disease and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and peptide YY receptor activity. | |
II. Introduction | |
Host Cell: | HEK293 |
Expressed gene: | GenBank accession number NM_000647.3; no expressed tags |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | C-C chemokine receptor type 2, CCR2 |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+400ug/ml G418 |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for NPY4R receptor |
Transducer: | Gi |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
Ⅳ.Representative Data | |
Concentration-dependent stimulation of intracellular calcium mobilization by MCP-1 in CCR2/Ga16/HEK293 and HEK293 cells. | |
Figure 1. MCP-1-induced concentration-dependent stimulation of intracellular calcium mobilization in CCR2/Ga16/HEK293 and HEK293 cells. The cells were loaded with Calcium-4 prior to stimulation with an CCR2 receptor agonist, MCP-1. The intracellular calcium change was measured by FlexStation. |