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药靶细胞株 > GPCR细胞株 > CBP71328NPY4R/Ga16/CHO

NPY4R/Ga16/CHO
名称 NPY4R/Ga16/CHO
型号 CBP71328
报价
特点 NPY4R/Ga16/CHO 冻存条件:90% FBS+10% DMSO,培养基:F12K+10%FBS+400ug/ml G418
  • 详细内容
CBP71328
I. Background

NPY4R (Neuropeptide Y Receptor Y4) is a Protein Coding gene. Diseases associated with NPY4R include Alzheimer Disease and Autosomal Recessive Non-Syndromic Intellectual Disability. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and peptide YY receptor activity.

 
II. Introduction
Host Cell:

HEK293

Expressed gene:GenBank accession number NM_000647.3; no expressed tags
Stability:32 passages
Synonym(s):

C-C chemokine receptor type 2, CCR2

Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+400ug/ml G418
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for NPY4R receptor

Transducer:Gi
 
Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epitheloid cell
Growth Properties: Adherent
 
Ⅳ.Representative Data

Concentration-dependent stimulation of intracellular calcium mobilization by MCP-1 in CCR2/Ga16/HEK293 and HEK293 cells.

 

Figure 1. MCP-1-induced concentration-dependent stimulation of intracellular calcium mobilization in CCR2/Ga16/HEK293 and HEK293 cells. The cells were loaded with Calcium-4 prior to stimulation with an CCR2 receptor agonist, MCP-1. The intracellular calcium change was measured by FlexStation.

 

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