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药靶细胞株 > GPCR细胞株 > CBP71311GCGR/Ga16/HEK293

GCGR/Ga16/HEK293
名称 GCGR/Ga16/HEK293
型号 CBP71311
报价
特点 GCGR/Ga16/HEK293 冻存条件:90% FBS+10% DMSO,培养基:DMEM+10%FBS+400ug/ml G418
  • 详细内容
CBP71311
I. Background

Glucagon regulates blood glucose via control of hepatic glycogenolysis and gluconeogenesis and via regulation of insulin release from the β cell. Pharmacological administration of glucagon increases blood glucose in normal and diabetic subjects, and produces positive inotropic and chronotropic cardiovascular effects, relaxation of smooth muscle in the gastrointestinal tract and stimulation of growth hormone secretion. The actions of glucagon are mediated via a single adenylate cyclase-coupled glucagon receptor that also couples to the phospholipase Cinositol phosphate (PLC-IP) pathway leading to Ca2+ release from intracellular stores.

 
II. Introduction
Host Cell:

HEK293/GCGR/Ga16

Stability:20 passages
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+400ug/ml G418
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for GCGR receptor

Transducer:Gs
 
Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:
Embryonic kidney
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data
 

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