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药靶细胞株 > GPCR细胞株 > CBP71320GLP1R/Ga16/HEK293

GLP1R/Ga16/HEK293
名称 GLP1R/Ga16/HEK293
型号 CBP71320
报价
特点 GLP1R/Ga16/HEK293 冻存条件:90% FBS+10% DMSO,培养基:DMEM+10%FBS+400ug/ml G418
  • 详细内容
RQP71320 GLP1R/Ga16/HEK293
I. Background

GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently, GLP1R has been suggested as a potential target for the treatment of diabetes. GLP1R is also expressed in the brain where it is involved in the control of appetite. Furthermore, mice which over express GLP1R display improved memory and learning.

 
II. Introduction
Host Cell:

HEK293

Stability:20 passages
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+400ug/ml G418
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for GLP1R receptor

 
Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:kidney
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

Figure 1.Calcium Mobilizaiton Assay GLP1R/ Ga16/293.

 

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