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药靶细胞株 > GPCR细胞株 > CBP71317MC3R/Luc/HEK293

MC3R/Luc/HEK293
名称 MC3R/Luc/HEK293
型号 CBP71317
报价
特点 MC3R/Luc/HEK293 冻存条件:90% FBS+10% DMSO
  • 详细内容
CBP71317
I. Background

The melanocortin receptor 3 (MC3 receptor) is Gs-coupled GPCRs expressed in brain, placental, and gut tissues but not in melanoma cells or in the adrenal gland. MC3 receptor knockouts exhibit a metabolic syndrome. At 4-6 months old, MC3 receptor knockout mice show increased fat mass, reduced lean mass and a higher feed efficiency, with normal metabolic rates. MC3 knockout mice are hyperleptinaemic and males are often mildly hyperinsulinaemic. GenScript's cloned human MC3R-expressing cell line is made in the 293/CRE-Luciferase host.

 
II. Introduction
Host Cell:

HEK293

Stability:20 passages
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+400ug/ml G418
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for MC3 receptor

Transducer:Gs
 
Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:kidney
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data
 

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