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药靶细胞株 > kinase激酶细胞株 > CBP73047EGFR L858R-C797S/BaF3 kinase细胞株

EGFR L858R-C797S/BaF3 kinase细胞株
名称 EGFR L858R-C797S/BaF3 kinase细胞株
型号 CBP73047
报价
特点 EGFR L858R-C797S/BaF3
  • 详细内容

 

CBP73047
I. Introduction

Cell Line Name:

EGFR L858R-C797S/BaF3

Gene Synonyms:

ERBB, mENA, ERBB1, HER1 

Host Cell:

Ba/F3

Stability:16 passages

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

1640+10%FBS

Mycoplasma Status:

Negative

 
II.Background

EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.EGFR D770_N771insG results in the insertion of a glycine (G) in the protein kinase domain of the Egfr protein between amino acids 770 and 771 (UniProt.org). D770_N771insG has not been biochemically characterized, but is predicted to result in a gain of function based on the effect of other Egfr exon 20 insertions.

 
III. Representative Data

1.Sanger of EGFR L858R-C797S/BaF3

Figure 1. EGFR L858R-C797S/BaF3 C797S

Figure 2. EGFR L858R-C797S/BaF3 L858R

2. Anti-proliferation assay

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