名称 | NRAS p.Q61R Reference Standard 标准品 |
型号 | CBP10309 |
报价 | |
特点 | NRAS p.Q61R Reference Standard |
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CBP10309 | |
Format | Genomic DNA |
Description | NRAS Q61R is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). Q61R results in a loss of Nras GTPase function as indicated by increased GTP-bound Nras, which leads to activation of Mapk signaling in culture (PMID: 16818621). |
Technical Data | |
DNA Change | c.182A>G |
AA Change | p.Q61R |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000369535 |
Cosmic ID | COSM584 |
Chr position(GRCh37) | chr1:115256529 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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