名称 | TP53 p.APSWPLSSS88fs Reference Standard 标准品 |
型号 | CBP10447 |
报价 | |
特点 | TP53 p.APSWPLSSS88fs Reference Standard |
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电话:4008750250
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手机:18066071954
地址:南京市栖霞区纬地路9号
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CBP10447 | |
Gene | TP53 |
Description | TP53, cellular tumor antigen p53, is a tumor suppressor (PMID: 30562755) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types cancers (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
Technical Data | |
DNA Change | c.261_286del |
AA Change | p.APSWPLSSS88fs |
Mutation type | Frame_Shift_Del |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000420246.2 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr17:7579426_7579401 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | Download for COA |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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