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药靶细胞株 > kinase激酶细胞株 > CBP73227KRAS G12C/BaF3

KRAS G12C/BaF3
名称 KRAS G12C/BaF3
型号 CBP73227
报价
特点 KRAS G12C/BaF3,母细胞:BaF3,冻存条件:90% FBS+10% DMSO,培养基:1640+10%FBS+2ug/ml puromycin
  • 详细内容

 

CBP73227
I. Introduction

Cell Line Name:

KRAS G12C/BaF3

Gene Synonyms:

KRAS

Host Cell:

Ba/F3

Stability:16 passages

Application:

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

1640+10%FBS+2ug/ml puromycin

Mycoplasma Status:

Negative

 
II.Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

 
III. Representative Data

1.WB of KRAS G12C/BaF3

CBP73227 WB.png

 

2.Sanger of KRAS G12C/BaF3

CBP73227 sanger.png

 

3. Anti-proliferation assay

 

Figure 3. Anti-proliferation assay of two reference compounds on the KRAS G12C/BaF3 Stable Cell Line.


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