名称 | KRAS G12D/BaF3 |
型号 | CBP73228 |
报价 | |
特点 | KRAS G12D/BaF3,母细胞:BaF3,冻存条件:90% FBS+10% DMSO |
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药靶细胞株 > kinase激酶细胞株 > CBP73228KRAS G12D/BaF3
- 详细内容
CBP73228 | |
I. Introduction | |
Cell Line Name: | KRAS G12D/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin |
Mycoplasma Status: | Negative |
II.Background | |
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118). | |
III. Representative Data | |
1.WB of KRAS G12D/BaF3 | |
2.Sanger of KRAS G12D/BaF3 | |
3. Anti-proliferation assay Figure 3. CTG Proliferation Assay of BaF3 KRAS G12D Cells (C6). |