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药靶细胞株 > kinase激酶细胞株 > CBP73228KRAS G12D/BaF3

KRAS G12D/BaF3
名称 KRAS G12D/BaF3
型号 CBP73228
报价
特点 KRAS G12D/BaF3,母细胞:BaF3,冻存条件:90% FBS+10% DMSO
  • 详细内容
CBP73228
I. Introduction

Cell Line Name:

KRAS G12D/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+1ug/ml puromycin

Mycoplasma Status:

Negative

II.Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

III. Representative Data

1.WB of KRAS G12D/BaF3

CBP73228 WB新.png



2.Sanger of KRAS G12D/BaF3

CBP73228 新 9.13 Sanger.png

3. Anti-proliferation assay

CBP73228 新 9.13 数据图.jpg


Figure 3. CTG Proliferation Assay of BaF3 KRAS G12D Cells (C6).


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