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药靶细胞株 > kinase激酶细胞株 > CBP73265NCOA4-RET/BaF3

NCOA4-RET/BaF3
名称 NCOA4-RET/BaF3
型号 CBP73265
报价
特点 NCOA4-RET/BaF3,母细胞:BaF3,冻存条件:90% FBS+10% DMSO,培养基:1640+10%FBS
  • 详细内容

 

CBP73265
I. Introduction

Cell Line Name:

NCOA4-RET/BaF3

Gene Synonyms:

NCOA4

Host Cell:

BA/F3

Stability:16 passages

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

1640+10%FBS

Mycoplasma Status:

Negative

 
II.Background

NCOA4, nuclear receptor coactivator 4, is an androgen receptor coactivator (PMID: 15166229) and autophagy receptor that degrades ferritin complexes (PMID: 31061094) and plays a role in iron homeostasis (PMID: 30930742). NCOA4 fusions are frequently observed with RET in papillary thyroid carcinoma (also referred to as RET/PTC3) (PMID: 25731779) and have been reported in salivary intraductal carcinoma (PMID: 31162284), spindle cell tumors (PMID: 30938880), breast cancer (PMID: 30446652), colorectal cancer (PMID: 30210625), and lung cancer (PMID: 30038711).

 
III. Representative Data

1. WB of  NCOA4-RET/BaF3

   

CBP73265 WB.png

   

2. Anti-proliferation assay

Figure 2. CTG assay of  for NCOA4-RET/BaF3 Stable Cell Line.


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