名称 | HVEM/CHO |
型号 | CBP74037 |
报价 | ![]() |
特点 | HVEM/CHO,冻存条件:90% FBS+10% DMSO; |
产品搜索
相关文章
联系我们
联系人:蒋经理
电话:86-25-86880024
号码:86-25-86880024
手机:18066071954
地址:南京市雨花区长虹路222号
Email: duhaitao@cobioer.com
电话:86-25-86880024
号码:86-25-86880024
手机:18066071954
地址:南京市雨花区长虹路222号
Email: duhaitao@cobioer.com
产品展示 / PRODUCTS

- 详细内容
HVEM/CHO
CBP74037 | |
I. Background | |
HVEM (CD270, TNFRSF14) is a human cell surface receptor in the TNF-receptor superfamily that can act as both a co-stimulatory receptor and a co-inhibitory receptor expressed on the surface of T cells. Binding of HVEM to one of its ligands, LIGHT (CD258, TNFSF14) or LTα (lymphotoxin-α), causes a co-stimulatory signal which can activate lymphoid cells. Interaction with BTLA (CD272) or CD160 causes a co-inhibitory signal which negatively regulates T-cell immune responses. HVEM has also been shown to interact with adaptor proteins TRAF2 and TRAF5, and is critical to herpes simplex virus (HSV) cellular entry. | |
II. Description | |
Recombinant CHO stably expressing human HVEM (TNF receptor superfamily member 14; TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; GenBank Accession #NM_003820). | |
III. Introduction | |
Host Cell: | CHO |
Expressed gene: | HVEM |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | HVEM, TNFRSF14, CD270, HVEA, TR2, LIGHTR |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12k+10%FBS+400ug/ml zeocine |
Application(s): | Binding Assay,FACS |
Storage: | Liquid nitrogen |
IV. Description of Host Cell Line | |
Organism: | Cricetulus griseus, hamster, Chinese |
Tissue: | Ovary |
Disease: | Hamster Chinese ovary |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
Ⅴ. Representative Data | |
Figure 1. Recombinant CHO stably expressing human HVEM (TNF receptor superfamily member 14; TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; GenBank Accession #NM_003820). |