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药靶细胞株 > kinase激酶细胞株 > CBP73183EGFR D770>GY/BaF3

EGFR D770>GY/BaF3
名称 EGFR D770>GY/BaF3
型号 CBP73183
报价
特点 EGFR D770>GY/BaF3
  • 详细内容
CBP73183
I. Introduction

Cell Line Name:

EGFR D770>GY/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

II.Background

EGFR is the receptor for members of the EGF family and is a transmembrane glycoprotein that has tyrosine kinase activity.EGFR D770_N771insG results in the insertion of a glycine (G) in the protein kinase domain of the Egfr protein between amino acids 770 and 771 (UniProt.org). D770_N771insG has not been biochemically characterized, but is predicted to result in a gain of function based on the effect of other Egfr exon 20 insertions.

III. Representative Data

1. WB of EGFR D770>GY/BaF3

2. Anti-proliferation assay


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