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药靶细胞株 > kinase激酶细胞株 > CBP73324EZR-ROS1/BaF3

EZR-ROS1/BaF3
名称 EZR-ROS1/BaF3
型号 CBP73324
报价
特点 EZR-ROS1/BaF3
  • 详细内容


CBP73324                
I. Introduction                

Cell Line Name:                    

EZR-ROS1/BaF3                    

Host Cell:                    

Ba/F3                    

Stability:                16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)                

Application:                    

Anti-proliferation assay and PD assay                    

Freeze Medium:                    

90% FBS+10% DMSO                    

Complete Culture Medium:                    

RPMI-1640+10%FBS                    

Mycoplasma Status:                    

Negative                    


II.Background                
EZR, ezrin, is a member of the ERM family that links the cytoplasm to the actin cytoskeleton and regulates polarization and migration in leukocytes and macrophages. EZR plays a role in metastasis in a number of cancer types although decreased Ezr expression has been associated with decreased survival in clear cell renal carcinoma and an EZR-ROS1 fusion has been identified in lung cancer.                

III. Representative Data                

1.Sanger of EZR-ROS1/BaF3                    

                   

2. Anti-proliferation assay                    

                   

Figure 2. CTG Proliferation Assay of BaF3 EZR-ROS1 (C5).                    








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