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基因检测标准品 > Mutation > CBP10531TP53 p.K319* Reference Standard 标准品

TP53 p.K319* Reference Standard 标准品
名称 TP53 p.K319* Reference Standard 标准品
型号 CBP10531
报价
特点 TP53 p.K319* Reference Standard
  • 详细内容
CBP10531
FormatGenomic DNA
DescriptionTP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457).
  
Technical Data 
DNA Change

c.955A>T

AA Changep.K319* 
Mutation typeNonsense_Mutation
Zygosity

Homozygous

Allelic Frequency

100%

Transcript

ENST00000269305.4

Cosmic IDCOSM11658
Chr position(GRCh37)chr17:7576891
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10531.png

Storage4°C
Expiry36 months from the date of manufacture

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