| 名称 | FGFR3-TACC3 K650N /BaF3细胞株 |
| 型号 | CBP73377 |
| 报价 |  |
| 特点 | FGFR3-TACC3 [K650N] /BaF3 |
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药靶细胞株 > kinase激酶细胞株 > CBP73377FGFR3-TACC3 K650N /BaF3细胞株
- 详细内容
| CBP73377 | |
| I. Introduction | |
Cell Line Name： | FGFR3-TACC3 [K650N] /BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
FGFR3-TACC3 results from the fusion of FGFR3 and TACC3, demonstrating constitutive kinase activity, transforming activity in culture and ability to drive tumor growth in xenografts (PMID: 25294908, PMID: 22837387). FGFR3-TACC3 has been identified in lung adenocarcinoma and glioblastoma (PMID: 25294908, PMID: 22837387). | |
| III. Representative Data | |
1.WB of FGFR3-TACC3 [K650N] /BaF3
| |
2. Sanger of FGFR3-TACC3 [K650N] /BaF3
Figure 2. FGFR3-TACC3 [K650N] /BaF3 K650N
Figure 3. FGFR3-TACC3 [K650N] /BaF3 FGFR3-TACC3 | |
3. Anti-proliferation assay
Figure 4. CTG Proliferation Assay of BaF3 FGFR3-TACC3 K650N Cells (C3). | |
![CBP73377 sanger-K650N [K650N]FGFR3-TACC3 Baf3.jpg](https://img69.chem17.com/gxhpic_a89b1029a6/33c3386a40defc475760f2d932f284033cb8b6e22f4d3332c99606fa20a5b6639ca17b0d7b44af91.jpg "CBP73377 sanger-K650N [K650N]FGFR3-TACC3 Baf3.jpg")
