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基因检测标准品 > 其他类别 > CBP90040Package-Ref™ MRD Cocktail Reference Standard

Package-Ref™ MRD Cocktail Reference Standard
名称 Package-Ref™ MRD Cocktail Reference Standard
型号 CBP90040
报价
特点 Package-Ref™ MRD Cocktail Reference Standard
  • 详细内容
Package-RefTM MRD Cocktail Reference Standard
Cat No.CBP90040
DescripitionMRD是指治疗后体内残留的肿瘤细胞或者标志物,通常的翻译有3种,微小残留病灶(Minimal Residual Disease)、可检测残留病灶(Measurable Residual Disease)、分子残留病灶(Molecular Residual Disease)。
      
产品说明
货号名称%AF规格浓度备注
CBP90040-1Package-RefTM MRD Cocktail Reference Standard-0.5%0.50%500 ng/vial20 ng/µLOptimized ddPCR assay
CBP90040-2Package-RefTM MRD Cocktail Reference Standard-0.05%0.05%500 ng/vial20 ng/µLDilution fold-confirmation
CBP90040-3Package-RefTM MRD Cocktail Reference Standard-0.005%0.005%500 ng/vial20 ng/µLDilution fold-confirmation
CBP90040-4Package-RefTM MRD Cocktail Reference Standard-0%0.00%500 ng/vial20 ng/µLddPCR assay
      
MRD-0.5% ctDNA
GENEMut.CDS changeVariant ClassificationAF%
EGFRp.E746_A750delELREAc.2236_2250del15
GAATTAAGAGAAGCA>-
Pathogenic0.69
EGFRp.S768Ic.2303G>TPathogenic0.61
EGFRp.L861Qc.2582T>APathogenic0.61
ERBB2p.A775_G776insYVMAc.2324_2325ins12
ATACGTGATGGC
Pathogenic0.41
KRASp.G12Vc.35G>TPathogenic0.39
PIK3CAp.E542Kc.1624G>APathogenic0.62
KRASp.Q61Hc.183A>CPathogenic0.49
EGFRp.G719Cc.2155G>TPathogenic0.5
ROS1CD74-ROS1chr5:149783684:- (hg19)
chr6:117646732:- (hg19)
Pathogenic0.55
NRASp.Q61Kc.181C>APathogenic0.41
IDH1p.R132Cc.394C>TPathogenic0.43
FBXW7p.R505Cc.1513C>TPathogenic0.75
KMT2Cp.F4496Lfs*21c.13488delALikely Pathogenic0.46
RAC1p.N92Ic.275A>TPathogenic0.4
BCORp.Q1321*c.3961C>TLikely Pathogenic0.68
BRCA2p.M784Vc.2350A>GBenign0.64
ARID1Ap.G1848Wfs*6c.5540dupGLikely Pathogenic0.61
CDH1p.P126Rfs*89c.377delCPathogenic0.74
BARD1p.K208Rfs*4c.623delTLikely Pathogenic0.38
BAXp.E41Rfs*19c.121delGPathogenic0.75
NBNp.R466Gfs*18c.1396delTPathogenic0.71
KMT2Dp.Q809Rfs*121c.2425delGLikely Pathogenic0.51
KMT2Dp.P647Hfs*283c.1940delGPathogenic0.44
QKIp.K134Rfs*14c.401delALikely Pathogenic0.63
KMT2Bp.W336*c.1007G>ALikely Pathogenic0.75
NSD1p.M1531Cfs*43c.4591delALikely Pathogenic0.74
AXIN1p.E31*c.91G>TLikely Pathogenic0.66
AXIN1p.G508Vfs*197c.1523delLikely Pathogenic0.69
ARID1Bp.A547Sfs*35c.1638_1647del
GGGCGGCGGC
Pathogenic0.47
HLA-Bp.S101Pfs*37c.301_302delLikely Pathogenic  0.66
HLA-Cp.V100Efs*38c.299_300delTGLikely Pathogenic0.51
TP53BP1p.R1447Efs*36c.4339delCLikely Pathogenic0.57
POLD1N/Ac.E24-2AG>ALikely Pathogenic0.73
CYLDp.N722Mfs*13c.2165delALikely Pathogenic0.57
INHAp.G66Afs*61c.197delGLikely Pathogenic 0.74
RASA1p.N838Mfs*4c.2513delALikely Pathogenic0.51
RECQL4p.G952Afs*92c.2855delGLikely Pathogenic0.54
BRAFp.V600Ec.1799T>APathogenic5.33
ACVR2Ap.K437Rfs*5c.1310delALikely Pathogenic3.98
PIK3CAp.H1047Rc.3140A>GPathogenic2.81
BRCA1p.D435Yc.1303G>TUncertain significance2.53
BRCA2p.N1784Tfs*7c.5351delAPathogenic2.35
BRCA2p.E2292Ac.6875A>CUncertain significance1.35
TP53N/Ac.783-2A>CPathogenic1.02
CDKN2Ap.R80*c.238C>TPathogenic0.92
HLA-Ap.R45Afs*32c.133delLikely Pathogenic1.25
      
稀释倍数验证数据
GENEMutationAF% of MRD-0.5% ctDNAAF% of MRD-0.05% ctDNAAF% of MRD-0.005% ctDNA
BRAFp.V600E5.330.54 0.047
ACVR2Ap.K437Rfs*53.980.40 0.038
PIK3CAp.H1047R2.810.26 N/A
BRCA1p.D435Y2.530.24 N/A
BRCA2p.N1784Tfs*72.350.23 N/A
BRCA2p.E2292A1.350.14 N/A
TP53c.783-2A>C1.020.11 N/A
CDKN2Ap.R80*0.920.10N/A
HLA-Ap.R45Afs*321.250.11N/A

 

Product Information 

Intended UseResearch Use Only
Unit Size4支/套,0.5μg/支,20ng/μL
Storage-20℃
Expiry36 months from the date of manufacture

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