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药靶细胞株 > kinase激酶细胞株 > CBP73372KRAS G12C-R68M/BaF3 Kinase

KRAS G12C-R68M/BaF3 Kinase
名称 KRAS G12C-R68M/BaF3 Kinase
型号 CBP73372
报价
特点 KRAS G12C-R68M/BaF3 Kinase
  • 详细内容
CBP73372
I. Introduction

Cell Line Name:

KRAS G12C-R68M/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS+2ug/ml puromycin

Mycoplasma Status:

Negative

II.Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

III. Representative Data

1.Sanger of KRAS G12C-R68M/BaF3

CBP73372 sanger-1.jpg

Figure 1. KRAS(NM_033360.4):c.34G>T p.G12C

CBP73372 sanger-2.jpg

Figure 2. KRAS(NM_004985.5): c.203G>T  p.R68M

2. Anti-proliferation assay

CBP73372 数据图.jpg

Figure 3. CTG Proliferation Assay of KRAS G12C/R68M BaF3 Cells (C2).




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