加入收藏 | 设为首页 | 联系我们

产品搜索

相关文章

联系我们

联系人:蒋经理
电话:86-25-86880024
号码:86-25-86880024
手机:18066071954
地址:南京市雨花区长虹路222号
Email: duhaitao@cobioer.com

产品展示 / PRODUCTS
药靶细胞株 > 免疫治疗细胞株 > CBP74021TLR8/NFkB-Luc/HEK293

TLR8/NFkB-Luc/HEK293
名称 TLR8/NFkB-Luc/HEK293
型号 CBP74021
报价
特点 TLR8/NFkB-Luc/HEK293,冻存条件:90% FBS+10% DMSO;培养基:MEM + 10% Foetal Bovine Serum (FBS)+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) +1ug/ml puromycin+100ug/ml hygromycin
  • 详细内容

 TLR8/NFkB-Luc/HEK293

CBP74021
I. Background
The TLR family plays a fundamental role in pathogen recognition and activation of innate immunity. TLR8 is an endosomal receptor that recognizes single stranded RNA (ssRNA), and can recognize ssRNA viruses such as Influenza, HIV and HCV. TLR8 binding to the viral RNA recruits MyD88 and leads to activation of the transcription factor NFκB and an antiviral response. Human TLR8 is functional but murine TLR8 is non-functional because it lacks five amino acids.
 
II. Description

Recombinant HEK293 cell expressing firefly luciferase gene under the control of NFkB response elements with constitutive expression of human TLR8 (Toll-like receptor 8, also known as CD288, a member of the toll-like receptor (TLR) family (GenBank Accession No. NM_138636).

 
III. Introduction
Host Cell:NFAT reporter Jurkat cells
Expressed gene:TLR8
Stability:32 passages
Synonym(s):CD288, TLR8, Toll-like receptor 8, tlr, tlr-8 TLR, nfkb, nf-kb reporter TLR
Freeze Medium:90% FBS+10% DMSO
Culture Medium:MEM + 10% Foetal Bovine Serum (FBS)+ 1% Non Essential Amino Acids (NEAA) + 1mM Sodium Pyruvate (NaP) +1ug/ml puromycin+100ug/ml hygromycin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Screen for activators or inhibitors of TLR8 signaling in a cellular context • Characterize the biological activity of TLR8 and its interactions with ligands
 
IV. Description of Host Cell Line
Organism:Human
Tissue:kidney
Morphology: Epitheloid cell
Growth Properties: Adherent
 
Ⅴ. Representative Data

 

Figure 1. Recombinant HEK293 cell line expressing firefly luciferase gene under the control of  NFκB response elements with constitutive expression of TLR8.

 

如果你对CBP74021TLR8/NFkB-Luc/HEK293感兴趣,想了解更详细的产品信息,填写下表直接与厂家联系:


留言框

  • 产品:

  • 您的单位:

  • 您的姓名:

  • 联系电话:

  • 常用邮箱:

  • 省份:

  • 详细地址:

  • 补充说明:

  • 验证码:

    请输入计算结果(填写阿拉伯数字),如:三加四=7
QQ在线客服
电话咨询
  • 25-86880024
  • 手机:18066071954

化工仪器网

推荐收藏该企业网站
扫一扫访问手机站扫一扫访问手机站
访问手机站