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药靶细胞株 > kinase激酶细胞株 > CBP73236c-Kit D820Y/BaF3

c-Kit D820Y/BaF3
名称 c-Kit D820Y/BaF3
型号 CBP73236
报价
特点 c-Kit D820Y/BaF3
  • 详细内容

CBP73236

I. Introduction

Cell Line Name:

c-Kit D820Y/BaF3

Host Cell:

Ba/F3

Stability:16 passages

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

 

Mycoplasma Status:

Negative

 
II.Background

KIT D820Y lies within the protein kinase domain of the Kit protein (UniProt.org). D820Yresuts in constitutive phosphorylation of Kit and is transforming in cell culture (PMID: 19035443, PMID: 11984533), and has also been identified as a secondary mutation associated with imatinib-resistance (PMID: 18488160).

 
III. Representative Data

1. WB of c-Kit D820Y/BaF3

 

2.Sanger of c-Kit D820Y/BaF3

 

3. Anti-proliferation assay

 

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