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药靶细胞株 > 肿瘤免疫细胞株 > CBP74147PDL1/MHCII APC Cell

PDL1/MHCII APC Cell
名称 PDL1/MHCII APC Cell
型号 CBP74147
报价
特点 PDL1/MHCII APC Cell 冻存条件:90% FBS+10% DMSO
  • 详细内容


CBP74147
I. Background
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. diabetes.
II. Introduction
Expressed gene:PD1、LAG3
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin+10ug/ml blasticidin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
III. Representative Data


Figure 1. Dose Response of Blocking Antibodies in PD-1/LAG3 Dual Effector Reporter Cells (C15) With PD-L1/MHCII APC Cells.





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