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基因检测标准品 > Mutation > CBP10427AI-Edigene® BRAF p.V600G Reference Standard P

AI-Edigene® BRAF p.V600G Reference Standard P
名称 AI-Edigene® BRAF p.V600G Reference Standard P
型号 CBP10427
报价
特点 AI-Edigene® BRAF p.V600G Reference Standard Plus
  • 详细内容
 CBP10427
FormatGenomic DNA
DescriptionBRAF, serine/threonine-protein kinase B-raf, is a member of the Raf family of serine/threonine protein kinases, which signals through the MAP kinase pathway to regulate cell proliferation and cell growth (PMID: 24737949, PMID: 29540830). BRAF mutations have been identified in a variety of cancers, including, colorectal (PMID: 30122982), lung (PMID: 29729495), thyroid (PMID: 12970315), and melanoma (PMID: 24737949), and a number of mutations have also been demonstrated to confer drug resistance (PMID: 27478040).
  
Technical Data 
DNA Changec.1799T>G
AA Changep.V600G
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptENST00000288602
Cosmic IDCOSM6137
Chr position(GRCh37)chr7:140453136
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

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Storage4℃
Expiry36 months from the date of manufacture

 

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