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基因检测标准品 > Mutation > CBP10474AI-Edigene® ERBB2 p.V777_G778insCG Reference

AI-Edigene® ERBB2 p.V777_G778insCG Reference
名称 AI-Edigene® ERBB2 p.V777_G778insCG Reference
型号 CBP10474
报价
特点 AI-Edigene® ERBB2 p.V777_G778insCG Reference Standard Plus
  • 详细内容
 CBP10474
GeneERBB2
DescriptionERBB2 (HER2), erb-b2 receptor tyrosine kinase 2, is an EGFR receptor tyrosine kinase that activates PI3K-AKT-mTOR and RAS-RAF-MEK-ERK pathways, therefore regulating growth and transformation (PMID: 17471238). ERBB2 (HER2) amplification, overexpression, and activation has been implicated in several tumor types (PMID: 17471238).
  
Technical Data 
DNA Changec.2331_2332insTGTGGG
AA Changep.V777_G778insCG
Mutation typeIn_Frame_Ins
ZygosityHomozygous
Allelic Frequency100%
TranscriptNM_004448.3
Cosmic IDN/A
Chr position(GRCh37)chr17:37881002_37881003
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10474.png

Storage4℃
Expiry36 months from the date of manufacture

 

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