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基因检测标准品 > Mutation > CBP10270ERBB2 p.L755S Reference Standard 标准品

ERBB2 p.L755S Reference Standard 标准品
名称 ERBB2 p.L755S Reference Standard 标准品
型号 CBP10270
报价
特点 ERBB2 p.L755S Reference Standard
  • 详细内容
 CBP10270
FormatGenomic DNA
DescriptionERBB2 (HER2) L755S lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). L755S results in increased phosphorylation of Erbb2 (Her2), activation of downstream signaling, is transforming in cell culture (PMID: 29967253), and is associated with resistance to Erbb2 (Her2)-targeted therapies (PMID: 22046346, PMID: 28487443).
  
Technical Data 
DNA Changec.2264T>C
AA Changep.L755S
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency66.67%
TranscriptENST00000269571
Cosmic IDN/A
Chr position(GRCh37)chr17:37880220
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10270.png

Storage4℃
Expiry36 months from the date of manufacture
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