名称 | KRAS p.G12R Reference Standard 标准品 |
型号 | CBP10295 |
报价 | |
特点 | KRAS p.G12R Reference Standard |
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CBP10295 | |
Format | Genomic DNA |
Description | KRAS G12R is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12R results in decreased Kras GTPase activity and increased activation of downstream signaling in cell culture (PMID: 23455880, PMID: 26037647). |
Technical Data | |
DNA Change | c.34G>C |
AA Change | p.G12R |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000311936 |
Cosmic ID | COSM518 |
Chr position(GRCh37) | chr12:25398285 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |