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基因检测标准品 > Mutation > CBP10292KRAS p.G12D Reference Standard 标准品

KRAS p.G12D Reference Standard 标准品
名称 KRAS p.G12D Reference Standard 标准品
型号 CBP10292
报价
特点 KRAS p.G12D Reference Standard
  • 详细内容

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 CBP10292
FormatGenomic DNA
DescriptionKRAS G12D is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12D results in decreased Kras GTPase activity and increased activation of downstream signaling, promotes tumor formation in mouse models (PMID: 16474405, PMID: 26037647, PMID: 22871572) and is transforming in cell culture (PMID: 29533785).
  
Technical Data 
DNA Changec.35G>A
AA Changep.G12D
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptENST00000311936
Cosmic IDCOSM521
Chr position(GRCh37)chr12:25398284
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10292.png

Storage4℃
Expiry36 months from the date of manufacture

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