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基因检测标准品 > Mutation > CBP10538NPM1 p.R277W Reference Standard 标准品

NPM1 p.R277W Reference Standard 标准品
名称 NPM1 p.R277W Reference Standard 标准品
型号 CBP10538
报价
特点 NPM1 p.R277W Reference Standard
  • 详细内容

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 CBP10538
FormatGenomic DNA
DescriptionNPM1, nucleophosmin, is a phosphoprotein that shuttles between the nucleus and cytoplasm, and is involved in several cellular processes including ribosomal processing and export, chromatin remodeling, DNA replication and repair, and cell cycle control (PMID: 29157973, PMID: 23436734). NPM1 is frequently mutated in acute myeloid leukemia (PMID: 29157973, PMID: 23436734, PMID: 30122998, PMID: 29785446, PMID: 32203582, PMID: 32609823) and overexpression is implicated with poor prognosis in hematological and solid tumors (PMID: 32071709).
  
Technical Data 
DNA Changec.829C>T
AA Changep.R277W
Mutation typeMissense_Mutation
ZygosityHeterozygous
Allelic FrequencyN/A
TranscriptNM_002520.7
Cosmic IDCOSM3339473
Chr position(GRCh37)chr5:170834761
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencingDownload for COA
Storage4℃
Expiry36 months from the date of manufacture

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