| 名称 | PIK3CA p.C420R Reference Standard 标准品 | 
| 型号 | CBP10328 | 
| 报价 |  | 
| 特点 | PIK3CA p.C420R Reference Standard | 
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|  CBP10328 | |
| Format | Genomic DNA | 
| Description | PIK3CA C420R lies within the C2 PI3K-type domain of the Pik3ca protein (PMID: 17376864). C420R confers a gain of function on Pik3ca, as indicated by constitutive phosphorylation of downstream targets Akt and S6, and is transforming in cell culture (PMID: 17376864, PMID: 29533785). | 
| Technical Data | |
| DNA Change | c.1258T>C | 
| AA Change | p.C420R | 
| Mutation type | Substitution - Missense | 
| Zygosity | Heterozygous | 
| Allelic Frequency | 75.00% | 
| Transcript | NM_006218.1 | 
| Cosmic ID | COSM757 | 
| Chr position(GRCh37) | chr3:178927980 | 
| Buffer | Tris-EDTA | 
| Product Information | |
| Intended Use | Research Use Only | 
| Unit Size | 1ug | 
| Concentration | Download for COA | 
| Purofication | Download for COA | 
| DNA electrophoresis | Download for COA | 
| Sanger sequencing | 
 | 
| Storage | 4℃ | 
| Expiry | 36 months from the date of manufacture | 




