名称 | PIK3CA p.C420R Reference Standard 标准品 |
型号 | CBP10328 |
报价 | ![]() |
特点 | PIK3CA p.C420R Reference Standard |
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CBP10328 | |
Format | Genomic DNA |
Description | PIK3CA C420R lies within the C2 PI3K-type domain of the Pik3ca protein (PMID: 17376864). C420R confers a gain of function on Pik3ca, as indicated by constitutive phosphorylation of downstream targets Akt and S6, and is transforming in cell culture (PMID: 17376864, PMID: 29533785). |
Technical Data | |
DNA Change | c.1258T>C |
AA Change | p.C420R |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 75.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM757 |
Chr position(GRCh37) | chr3:178927980 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |