| 名称 | TP53 p.C135fs Reference Standard 标准品 |
| 型号 | CBP10438 |
| 报价 |  |
| 特点 | TP53 p.C135fs Reference Standard |
产品搜索
相关文章
联系我们
联系人：蒋经理
电话：4008750250
号码：
手机：18066071954
地址：南京市栖霞区纬地路9号
Email： zhangxiangwen@cobioer.com
电话：4008750250
号码：
手机：18066071954
地址：南京市栖霞区纬地路9号
Email： zhangxiangwen@cobioer.com
产品展示 / PRODUCTS
- 详细内容
CBP10438 | |
| Gene | TP53 |
| Description | TP53, cellular tumor antigen p53, is a tumor suppressor (PMID: 30562755) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types cancers (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
| Technical Data | |
| DNA Change | c.403delT |
| AA Change | p.C135fs |
| Mutation type | Frame_Shift_Del |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000269305.4 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr17:7578527 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
" _ue_custom_node_="true">
