| 名称 | TP53 p.C135fs*35 Reference Standard 标准品 |
| 型号 | CBP10170 |
| 报价 |  |
| 特点 | TP53 p.C135fs*35 Reference Standard |
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CBP10170 | |
| Format | Genomic DNA |
| Description | TP53 C135fs results in a change in the amino acid sequence of the Tp53 protein beginning at aa 135 of 393, likely resulting in premature truncation of the functional protein (UniProt.org). Due to disruption of the DNA-binding domain and loss of the oligomerization domain (UniProt.org), C135fs is predicted to lead to a loss of Tp53 protein function. |
| Technical Data | |
| DNA Change | c.403delT |
| AA Change | p.C135fs*35 |
| Mutation type | Deletion - Frameshift |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000269305 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr17:7578527 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
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| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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