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基因检测标准品 > Mutation > CBP10168TP53 p.C135Y Reference Standard 标准品

TP53 p.C135Y Reference Standard 标准品
名称 TP53 p.C135Y Reference Standard 标准品
型号 CBP10168
报价
特点 TP53 p.C135Y Reference Standard
  • 详细内容

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 CBP10168
FormatGenomic DNA
DescriptionTP53 C135Y lies within the DNA-binding domain of the Tp53 protein (UniProt.org). C135Y confers a loss of function to the Tp53 protein as demonstrated by loss of binding to the Drosha complex and inability to induce downstream miRs and loss of transactivation activity in cell culture (PMID: 19626115, PMID: 8336941).
  
Technical Data 
DNA Changec.404G>A
AA Changep.C135Y
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100%
TranscriptENST00000269305
Cosmic IDCOSM10801
Chr position(GRCh37)chr17:7578526
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10168.png

Storage4℃
Expiry36 months from the date of manufacture

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