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基因检测标准品 > Mutation > CBP10150TP53 p.C176F Reference Standard 标准品

TP53 p.C176F Reference Standard 标准品
名称 TP53 p.C176F Reference Standard 标准品
型号 CBP10150
报价
特点 TP53 p.C176F Reference Standard
  • 详细内容

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 CBP10150
FormatGenomic DNA
DescriptionTP53 C176F lies within a zinc binding residue in the DNA-binding region of the Tp53 protein (UniProt.org). C176F is predicted to confer a loss of function to the Tp53 protein, as demonstrated by the inability to induce CDKN1A (p21) transcription in cell culture (PMID: 22090360).
  
Technical Data 
DNA Change:c.527G>T
AA Changep.C176F
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency33.33%
TranscriptENST00000269305
Cosmic IDCOSM10645
Chr position(GRCh37)chr17:7578403
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencingDownload for COA
Storage4℃
Expiry36 months from the date of manufacture

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