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药靶细胞株 > GPCR细胞株 > CBP71384C5aR1/b-Arrestin/CHO 细胞

C5aR1/b-Arrestin/CHO 细胞
名称 C5aR1/b-Arrestin/CHO 细胞
型号 CBP71384
报价 86000
特点 C5aR1/b-Arrestin/CHO C5AR1 (Complement C5a Receptor 1) is a Protein Coding gene. Diseases associated with C5AR1 include Hypersensitivity Reaction Type Iii Disease and Mast-Cell Sarcoma. Among its rela
  • 详细内容
CBP71384                
I. Background                
C5AR1 (Complement C5a Receptor 1) is a Protein Coding gene. Diseases associated with C5AR1 include Hypersensitivity Reaction Type Iii Disease and Mast-Cell Sarcoma. Among its related pathways are Complement cascade and GPCR downstream signalling.                

II. Introduction                
Host Cell:                

CHO                    

Stability:                20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)                
Freeze Medium:                90% FBS+10% DMSO                
Culture Medium:                
Mycoplasma Status:                Negative                
Storage:                Liquid nitrogen immediately upon delivery                
Application(s):                

Functional assay for C5aR1 receptor                    

Transducer:                Gi                

Ⅲ. Description of Host Cell Line                
Organism:                Hamster                
Tissue:                Ovary                
Morphology:                Epithelial                
Growth Properties:                Adherent                

Ⅳ. Representative Data                

CBP71384-1.jpg                    

Figure 1.Dose response of Human C5a in C5aR1 β-Arrestin CHO-K1 Cell Line (C8).                    

CBP71384-2.jpg                    

Figure 2. Inhibition of hC5a-induced Beta-Arrestin Recruitment By hC5a Neutralization Ab in C5aR1 Beta-Arrestin CHO-K1Cells(C8).                    


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