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基因检测标准品 > 用药指导 > CBPA0045CYP2D6*2 Reference Standard

CYP2D6*2 Reference Standard
名称 CYP2D6*2 Reference Standard
型号 CBPA0045
报价
特点 CYP2D6*2 Reference Standard
  • 详细内容
CBPA0045 
FormatGenomic DNA
DescriptionCYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.
  
Technical Data 
GeneCYP2D6*2
Mutation Type 1AA Change: p.R296C    
DNA Change: NM_000106.6:c.886C>T
Chr position (GRCh38): NC_000022.11:g.42127941G>A
Mutation Type 2AA Change: p.S486T
DNA Change: NM_000106.6:c.1457G>C
Chr position (GRCh38):NC_000022.11:g.42126611C>G
Allelic Frequency50%
ZygosityHeterozygous
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBPA0045-1.png

Figure 1. CYP2D6*2 Reference Standard  p.R296C  

CBPA0045-2.png

Figure 2. CYP2D6*2 Reference Standard p.S486T

Storage4°C
Expiry36 months from the date of manufacture

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