名称 | hPD-L1/MC38 |
型号 | CBPG0001 |
报价 | ![]() |
特点 | hPD-L1/MC38 |
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联系人:蒋经理
电话:86-25-86880024
号码:86-25-86880024
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地址:南京市雨花区长虹路222号
Email: zhangxiangwen@cobioer.com
电话:86-25-86880024
号码:86-25-86880024
手机:18066071954
地址:南京市雨花区长虹路222号
Email: zhangxiangwen@cobioer.com
产品展示 / PRODUCTS

- 详细内容
CBPG0001 | |
I. Background | |
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. The PD-1:PD-L1/2 pathway is also involved in regulating autoimmune responses, making these proteins promising therapeutic targets for a number of cancers, as well as multiple sclerosis, arthritis, lupus, and type I diabetes. | |
II. Introduction | |
Host Cell: | MC38 |
Expressed gene: | hPD-L1 |
Stability: | 32 passages |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+5ug/ml blasticidin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
III. Description of Host Cell Line | |
Organism: | Mouse |
Tissue: | Colon |
Morphology: | Epitheloid cell |
Growth Properties: | Adherent |
IV. Representative Data | |
Figure 1. Recombinant hPD-L1/MC38 stably expressing hPD-L1. | |