KRAS G12C-A59T/BaF3 细胞株-南京科佰生物科技有限公司

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Email： zhangxiangwen@cobioer.com

CBP73380
I. Introduction
Cell Line Name：	KRAS G12C-A59T/BaF3
Host Cell:	Ba/F3
Stability:	16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Application:	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Freeze Medium:	90% FBS+10% DMSO
Complete Culture Medium:	RPMI-1640+10%FBS+2ug/ml puromycin
Mycoplasma Status:	Negative

II.Background
KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

III. Representative Data
1. Sanger of KRAS G12C-A59T/BaF3 Figure 1. KRAS G12C-A59T/BaF3 G12C Figure 2. KRAS G12C-A59T/BaF3 A59T
2. Anti-proliferation assay Figure 3. CTG Proliferation Assay of KRAS G12C/A59T BaF3 Cells (C13).