名称 | c-Kit Y823D/BaF3 |
型号 | CBP73208 |
报价 | |
特点 | c-Kit Y823D/BaF3,母细胞:BaF3,KIT Y823D 位于 Kit 蛋白 (UniProt.org) 的蛋白激酶结构域内。 Y823D 赋予 Kit 功能,如培养细胞中 Kit 的组成性磷酸化所示(PMID:14695343,PMID:20633291)。 |
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药靶细胞株 > kinase激酶细胞株 > CBP73208c-Kit Y823D/BaF3
- 详细内容
CBP73208 | |
I. Introduction | |
Cell Line Name: | c-Kit Y823D/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
KIT Y823D lies within the protein kinase domain of the Kit protein (UniProt.org). Y823D confers a gain of function on Kit, as indicated by constitutive phosphorylation of Kit in cultured cells (PMID: 14695343, PMID: 20633291). | |
III. Representative Data | |
1.WB of c-Kit Y823D/BaF3 | |
2.Sanger of c-Kit Y823D/BaF3 | |
3. Anti-proliferation assay Figure 3. CTG Proliferation Assay of BaF3 c-KIT Y823D (C1). | |
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