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药靶细胞株 > 肿瘤免疫细胞株 > CBP74105ADCP Bioassay Effector Cell FcγRIa_NFAT/Jurkat

ADCP Bioassay Effector Cell FcγRIa_NFAT/Jurkat
名称 ADCP Bioassay Effector Cell FcγRIa_NFAT/Jurkat
型号 CBP74105
报价
特点 ADCP Bioassay Effector Cell FcγRIa_NFAT/Jurkat,母细胞:Jurkat,冻存条件:90% FBS+10% DMSO
  • 详细内容


CBP74105
I. Background

Antibody-dependent cell-mediated phagocytosis (ADCP) is one of the important mechanisms of action for antibody drug development.


II. Introduction
Host Cell:Jurkat
Expressed gene:FcγRIa_NFAT
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):N/A
Freeze Medium:90% FBS+10% DMSO
Culture Medium:RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin
Storage:Immediately upon receipt, store in liquid nitrogen.
Application(s):Characterize the Fc effector function of antibodies.
III. Description of Host Cell Line
Organism:Human
Tissue:Peripheral blood
Disease: Childhood T acute lymphoblastic leukemia
Morphology: Lymphoblast
Growth Properties: Suspension
IV.Representative Data

CBP74105.png

Figure 1:Dose response of Rituximab in ADCP Bioassay Effector Cell FcyRla/NFAT Reporter-Jurkat (C11),the EC50 was 1.94ng/ml.



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