名称 | IL23 Effector Reporter Cell |
型号 | CBP74130 |
报价 | |
特点 | IL23 Effector Reporter Cell 冻存条件:90% FBS+10% DMSO |
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Email: zhangxiangwen@cobioer.com
电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
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- 详细内容
CBP74130 | |
I. Background | |
IL-23 is a member of the IL-12 cytokine family, which also includes members such as IL-12, IL-27, IL-35 and IL-39, which are a unique set of heterodimeric cytokines, It usually consists of an alpha chain subunit (p19, p28, or p35) and a beta chain subunit (p40 or Epstein-Barr virus-induced gene 3), and signals are transduced through the JAK/STAT pathway. | |
II.Introduction | |
Expressed gene: | IL23R |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | IL-23 Receptor protein, IL-23R protein;Interleukin-23 receptor, IL23R, IL-23 receptor, IL-23R |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM +10%FBS+2ug/ml puromycin+200ug/ml hygromycin+5ug/ml blasticidin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
III. Representative Data | |
Figure 1. Recombinant IL23 Effector Reporter Cell stably expressing IL23R. Figure 2. Recombinant IL23 Effector Reporter Cell stably expressing IL12β1. Figure 3.Dose Response of Recombinant Human IL23 in Human IL23 Effector Reporter Cells (C6). Figure 4.Inhibition of lL23-induced Reporter Activity by IL23 Neutralizing Antibody in IL23 Effector Reporter Cells (Clone6). | |