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药靶细胞株 > 肿瘤免疫细胞株 > CBP74130IL23 Effector Reporter Cell

IL23 Effector Reporter Cell
名称 IL23 Effector Reporter Cell
型号 CBP74130
报价
特点 IL23 Effector Reporter Cell 冻存条件:90% FBS+10% DMSO
  • 详细内容


CBP74130
I. Background
IL-23 is a member of the IL-12 cytokine family, which also includes members such as IL-12, IL-27, IL-35 and IL-39, which are a unique set of heterodimeric cytokines, It usually consists of an alpha chain subunit (p19, p28, or p35) and a beta chain subunit (p40 or Epstein-Barr virus-induced gene 3), and signals are transduced through the JAK/STAT pathway.
II.Introduction
Expressed gene:IL23R
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):IL-23 Receptor protein, IL-23R protein;Interleukin-23 receptor, IL23R, IL-23 receptor, IL-23R
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM +10%FBS+2ug/ml puromycin+200ug/ml hygromycin+5ug/ml blasticidin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
III. Representative Data

CBP74130 流式1.png

Figure 1. Recombinant IL23 Effector Reporter Cell stably expressing IL23R.

CBP74130 流式.png

Figure 2. Recombinant IL23 Effector Reporter Cell stably expressing IL12β1.


Figure 3.Dose Response of Recombinant Human IL23 in Human IL23 Effector Reporter Cells (C6).


Figure 4.Inhibition of lL23-induced Reporter Activity by IL23 Neutralizing Antibody in IL23 Effector Reporter Cells (Clone6).






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