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药靶细胞株 > GPCR细胞株 > CBP71346GIPR/CRE-Luc/HEK293

GIPR/CRE-Luc/HEK293
名称 GIPR/CRE-Luc/HEK293
型号 CBP71346
报价
特点 GIPR/CRE/HEK293
  • 详细内容
CBP71346
I. Background
The gastric inhibitory polypeptide receptor (GIP-R), also known as the glucose-dependent insulinotropic polypeptide receptor,which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

II. Introduction
Host Cell:

HEK293

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM +10%FBS+2ug/ml puromycin+200ug/ml hygromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Transducer: Gs

Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:
Embryonic kidney
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data


Figure 1. Recombinant GIPR/CRE-Luc/HEK293 stably expressing human GIPR.



Figure 2. GIPR/CRE Reporter - HEK293 Recombinant Cell Line (C37).


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