| 名称 | CD74-ROS1/BaF3 kinase细胞株 |
| 型号 | CBP73331 |
| 报价 |  |
| 特点 | CD74-ROS1/BaF3 |
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药靶细胞株 > kinase激酶细胞株 > CBP73331CD74-ROS1/BaF3 kinase细胞株
- 详细内容
CBP73331 | |
| I. Introduction | |
Cell Line Name： | CD74-ROS1/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
CD74, CD74 molecule, encodes for a type II integral membrane glycoprotein that acts as an MHC class II chaperone and plays a role in the signal transduction of pathways related to cell survival, proliferation (PMID: 16484589, PMID: 27058619), and the immune system (PMID: 30191677). Overexpression of Cd74 has been observed in gastrointestinal cancer (PMID: 21228923) and hematological cancers (PMID: 30191677), and CD74-ROS1 and CD74-NRG1 fusions have been identified in lung cancer (PMID: 22215748, PMID: 31027745, PMID: 29169524). | |
| III. Representative Data | |
1. Sanger of CD74-ROS1/BaF3
| |
2. Anti-proliferation assay | |
Figure 2. CTG Proliferation Assay of BaF3 CD74-ROS1 Cells (C1). | |
