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药靶细胞株 > kinase激酶细胞株 > CBP73331CD74-ROS1/BaF3 kinase细胞株

CD74-ROS1/BaF3 kinase细胞株
名称 CD74-ROS1/BaF3 kinase细胞株
型号 CBP73331
报价
特点 CD74-ROS1/BaF3
  • 详细内容



CBP73331

I. Introduction

Cell Line Name:

CD74-ROS1/BaF3

Host Cell:

Ba/F3

Stability:16 passages

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:


Mycoplasma Status:

Negative


II.Background

CD74, CD74 molecule, encodes for a type II integral membrane glycoprotein that acts as an MHC class II chaperone and plays a role in the signal transduction of pathways related to cell survival, proliferation (PMID: 16484589, PMID: 27058619), and the immune system (PMID: 30191677). Overexpression of Cd74 has been observed in gastrointestinal cancer (PMID: 21228923) and hematological cancers (PMID: 30191677), and CD74-ROS1 and CD74-NRG1 fusions have been identified in lung cancer (PMID: 22215748, PMID: 31027745, PMID: 29169524).


III. Representative Data

1. Sanger of  CD74-ROS1/BaF3



2. Anti-proliferation assay

Figure 2. CTG Proliferation Assay of BaF3 CD74-ROS1 Cells (C1).



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