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药靶细胞株 > GPCR细胞株 > CBP71361CALCR1/RAMP1/CRE-Luc/HEK293 GPCR细胞

CALCR1/RAMP1/CRE-Luc/HEK293 GPCR细胞
名称 CALCR1/RAMP1/CRE-Luc/HEK293 GPCR细胞
型号 CBP71361
报价
特点 CALCR1/RAMP1/CRE-Luc/HEK293
  • 详细内容
CBP71361
I. Background
CALCR (Calcitonin Receptor) is a Protein Coding gene. Diseases associated with CALCR include Osteoporosis and Bone Mineral Density Quantitative Trait Locus 15. Among its related pathways are Presynaptic function of Kainate receptors and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and transmembrane signaling receptor activity.

II. Introduction
Host Cell:

HEK293

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM + 10%FBS+200ug/ml hygromycin+1ug/ml puromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Transducer:N/A

Ⅲ. Description of Host Cell Line
Organism:Human
Tissue:kidney
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data

 COBIOER

Figure 1. Dose Response of Agonists in Human CALCRL/RAMP1 CRE Luc Reporter HEK293 Cells (C1).

 COBIOER

Figure 2. Inhibtion of αCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.

 COBIOER

Figure 3. Inhibition of βCGRP induced Reporter Activity by CGRP Neutralizing Antibodies in CALCRL&RAMP1 CRE Luc HEK293 Cells.




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