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基因检测标准品 > Mutation > CBP10502FGFR3 p.K650E Reference Standard 标准品

FGFR3 p.K650E Reference Standard 标准品
名称 FGFR3 p.K650E Reference Standard 标准品
型号 CBP10502
报价
特点 FGFR3 p.K650E Reference Standard
  • 详细内容
 CBP10502
FormatGenomic DNA
DescriptionFGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443).
  
Technical Data 
DNA Changec.1948A>G
AA Changep.K650E
Mutation typeMissense_Mutation
ZygosityHeterozygous
Allelic Frequency74%
TranscriptNM_000142.5
Cosmic IDN/A
Chr position(GRCh37)chr4:1807889
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10502.png

Storage4℃
Expiry36 months from the date of manufacture

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