名称 | FGFR3 p.K650E Reference Standard 标准品 |
型号 | CBP10502 |
报价 | |
特点 | FGFR3 p.K650E Reference Standard |
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手机:18066071954
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CBP10502 | |
Format | Genomic DNA |
Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
Technical Data | |
DNA Change | c.1948A>G |
AA Change | p.K650E |
Mutation type | Missense_Mutation |
Zygosity | Heterozygous |
Allelic Frequency | 74% |
Transcript | NM_000142.5 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr4:1807889 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |