名称 | FGFR3 p.S249C Reference Standard 标准品 |
型号 | CBP10422 |
报价 | |
特点 | FGFR3 p.S249C Reference Standard |
产品搜索
相关文章
联系我们
联系人:蒋经理
电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
电话:4008750250
号码:
手机:18066071954
地址:南京市栖霞区纬地路9号
Email: zhangxiangwen@cobioer.com
产品展示 / PRODUCTS
- 详细内容
CBP10422 | |
Format | Genomic DNA |
Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
Technical Data | |
DNA Change: | c.746C>G |
AA Change | p.S249C |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 85.00% |
Transcript | NM_000142.5 |
Cosmic ID | COSM715 |
Chr position(GRCh37) | chr4:1803568 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
" _ue_custom_node_="true">