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基因检测标准品 > Mutation > CBP10304KRAS p.A146T Reference Standard 标准品

KRAS p.A146T Reference Standard 标准品
名称 KRAS p.A146T Reference Standard 标准品
型号 CBP10304
报价
特点 KRAS p.A146T Reference Standard
  • 详细内容
 CBP10304
FormatGenomic DNA
DescriptionKRAS A146T is an exon four mutation that does not lie within any known functional domains of the Kras protein (UniProt.org). A146T decreases Kras GTPase activity, increases phosphorylation of Mek and Erk, and is transforming in cell culture and xenografts (PMID: 19075190, PMID: 20570890).
  
Technical Data 
DNA Changec.436G>A
AA Changep.A146T
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic Frequency88%
TranscriptNM_033360.4
Cosmic IDCOSM19404
Chr position(GRCh37)chr12:25378562
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10304.jpg

Storage4℃
Expiry36 months from the date of manufacture
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