名称 | PIK3CA p.E542K Reference Standard 标准品 |
型号 | CBP10324 |
报价 | |
特点 | PIK3CA p.E542K Reference Standard |
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手机:18066071954
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CBP10324 | |
Format | Genomic DNA |
Description | PIK3CA E542K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E542K results in increased phosphorylation of Akt, growth factor-independent cell survival, and is transforming in cell culture (PMID: 16533766, PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.1624G>A |
AA Change | p.E542K |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | NM_006218.1 |
Cosmic ID | COSM760 |
Chr position(GRCh37) | chr3:178936082 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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