名称 | PIK3CA p.E545A Reference Standard 标准品 |
型号 | CBP10323 |
报价 | ![]() |
特点 | PIK3CA p.E545A Reference Standard |
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- 详细内容
CBP10323 | |
Format | Genomic DNA |
Description | PIK3CA E545A is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545A confers a gain of function on the Pik3ca protein as demonstrated by increased phosphorylation of Akt and transformation in cell culture (PMID: 17376864, PMID: 29533785). |
Technical Data | |
DNA Change | c.1634A>C |
AA Change | p.E545A |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 74.8% |
Transcript | NM_006218.1 |
Cosmic ID | COSM12458 |
Chr position(GRCh37) | chr3:178936092 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |