名称 | TP53 p.R249S Reference Standard 标准品 |
型号 | CBP10156 |
报价 | |
特点 | TP53 p.R249S Reference Standard |
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CBP10156 | |
Format | Genomic DNA |
Description | TP53 R249S is a hotspot mutation within the DNA-binding domain of the Tp53 protein (PMID: 22713868). R249S results in decreased DNA binding and transactivation activity of Tp53, and confers context-dependent transforming ability in cell culture (PMID: 20212049, PMID: 20538734). |
Technical Data | |
DNA Change: | c.747G>C |
AA Change | p.R249S |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305 |
Cosmic ID | COSM10785 |
Chr position(GRCh37) | chr17:7577534 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |