| 名称 | CYP2D6*10 Reference Standard |
| 型号 | CBPA0072 |
| 报价 |  |
| 特点 | CYP2D6*10 Reference Standard |
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| CBPA0072 | |
| Format | Genomic DNA |
| Description | CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients. |
| Technical Data | |
| Gene | CYP2D6 |
| Mutation Type 1 | AA Change: p.S486T |
| DNA Change: NM_000106.6:c.1457G>C | |
| Chr position (GRCh38): chr22:42126611 | |
| Mutation Type 2 | AA Change: p.P34S |
| DNA Change: NM_000106.6:c.100C>T | |
| Chr position (GRCh38): chr22:42130692 | |
| Allelic Frequency | 100% |
| Zygosity | Homozygous |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Figure 1. CYP2D6*10 Reference Standard p.S486T
Figure 2. CYP2D6*10 Reference Standard p.P34S |
| Storage | 4°C |
| Expiry | 36 months from the date of manufacture |
